Skip to main content

A 15 year old boy with subclinical hypothyroidism and deranged thyroid profile is gaining weight

This is a HIPAA de-identified open-online-patient-record with initial information in patient's voice, posted here after collecting informed patient consent (form downloadable Click Here)  by BMJ Elective Student. 


When he was in class 7 (aged 12 years), he started to get lethargy, fatigue, low IQ, less active, angriness, increased hunger with increasing weight gain. When he was about to start his 8th standard classes, he was taken to a local doctor who diagnosed him with hypothyroidism. The local doctor prescribed him 50 mcg thyroxine and when he was taken to another doctor for a second opinion, the doctor increased the dose to 150 through 75 mcg. Which they continued with repeated follow-up and after checking with the tests. The dose was increased as per the doctor is due to his growing age (that doctor also said if he takes this medicines for 2 years, it will be cured). They continued at this dose (150 mcg) for 1.4 years followed by 175 mcg (due to derangement in the thyroid profile as evidenced by the reports) which he is continuing till now. He has no known family history for any thyroid disorders. After starting thyroxine therapy, he appeared to have decreased laziness for the first month. Then after no improvement was noticed and since then his weight has been increasing, which was 54 KG in February 2017 but has increased to 73.5 KG now.


After repeat history, his father mentioned that his birth was uncomplicated but had a low birth weight. As he grew up, he was attentive to his studies and active until the age of 12 years when he started developing the symptoms mentioned above. His father shared a concern that he started gaining weight after taking wysolone (10 days) prescribed for his cough (normal PFT followed by inhaler by another doctor as it was not relieving) by a local physician. This prednisolone was prescribed even before he was diagnosed with subclinical hypothyroidism. Since then his weight is increasing and now it is 73.5 KG and height is 5.65/7 feet. Recently doctor’s found an elevated systolic BP (140/80 mm Hg) [which his father reports may be due to anxiety from abnormal thyroid profile] and fatty liver disease on USG. His father also reports foul smelling urine recently. His bowel habits are normal.

1st report as on 7.2.17: 


1st prescription: 

2nd report as on 16.5.17:


2nd prescription:


3rd report as on 19.5.17:


4th report as on 23.6.18:


Prescription as on 23.6.18:


5th report as on 9.1.18: 


Latest prescription as on 9.10.18: 


URINE R/E and CBC reports are pending (will update asap available).




Concerns: 

1. His father is concerned and in a dilemma, if he is getting right management (right drugs, right dosages) of his son's problem!
2. He is also concerned if the current low TSH value will harm him as he is a student. 
3. Really looking for a fast response as time is just increasing his anxiety. 

Comments

Popular posts from this blog

55 years Old male with Bipolar affected disorder moving from depression to Manic to depression phase

Disclaimer:- This is a HIPAA de-identified open-online-patient-record with initial information in patient's voice, posted here December 2017 after collecting informed patient consent (form downloadable Click Here) This is a case of a 55 years old, diabetic, hypertensive patient who was diagnosed with Bipolar affected disorder since 1995. In 1995 due to financial loss he was attacked by this condition. He was seen by Dr. D. K Agarwala and diagnosed as BPAD-Depression phase and treated with lithium, sodium valporate, propranolol, Zeptol cr, Nitrosum - S.  With the treatment he was reasonably well but every 6 months of interval he appeared to have some disturbance like didn't want to talk to anybody, forgot to smile etc. They went to the doctor and treated accordingly and was continuing the treatment.  In the year of 2013, August he was diagnosed with BPAD-severe depression phase but, he was not responding well to the medications and then they went to NIMHANS for

Consent Forms

Hindi BMJ Consent form   Bengali BMJ Consent form English BMJ Consent form   Telegu BMJ Consent Form Telegu BMJ Consent Form   UDHC Consent Form                

drugs to avoid or use in terms of their pregnancy category

The optimal AEDs therapy of women with epilepsy who are of childbearing age is unclear because of a lack of conclusive data on the comparative teratogenicity of different antiseizure drugs and no antiepileptic drug has proven safe in pregnancy in terms of teratogenesis. Data on the comparative efficacy of various antiseizure drugs for controlling seizures during pregnancy are also quite limited, and there are no randomized trials in this setting. Treatment must be individualized for all patients. Women with epilepsy are classified as high risk during pregnancy and as there are no clear data indicating that any drug is without risk in pregnancy therefore, the antiseizure drug regimen should be optimized six months prior to planned conception.  Choice of antiepileptic drugs in women of childbearing age and  pregnant women with epilepsy:  1. T he antiseizure drug that stops seizures in a given patient is the one that should be used with an exception of valproate. 2.