62 years old man with non small cell adenocarcinoma and biomarker evaluation for targeted therapy

This is a HIPAA de-identified open-online-patient-record with initial information in patient's voice, posted here after collecting informed patient consent (form downloadable Click Here) by BMJ Elective Student.

The 62 year old man appears to have a non-small-cell lung (NSCLC) adenocarcinoma lung with cerebral metastasis and the doctors are looking to further test for bio-markers that may predict response to targeted precision Medicine.

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WhatsApp Discussion:
SC:should prophylactic cranial irradiation be performed in bronchial adenocarcinoma/NSCLC as is advocated for SCLC? Because this patient had a brain met

RB: Yes "traditionally, whole-brain radiation therapy (WBRT) has been the standard treatment for brain metastases with multiple intracranial lesions although studies have shown no overall survival benefit and no improvement in quality of life.
It's one of the reasons why oncologists currently have shifted to what are termed as precision Medicine approaches and one sees case reports where "small-molecule inhibitor of EGFR-TKI is used in lung adenocarcinoma with brain metastases showing EGFR mutation-positive with reasonable quality of life outcomes. This is perhaps what has also been planned for our patient in Tata memorial. Shreyas do you have his current update?

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